INTERNATIONAL: NATIONAL & KARNATAKA : Udupi’s Dr Naveen Salins is New Commissioner of Lancet Commission; to Lead Study on Cancer Crisis

The Lancet Commission has proudly announced the appointment of Dr Naveen Salins as their new Commissioner. Dr Salins, known for his exceptional contributions to the field of Palliative Medicine and Cancer Care, will spearhead a comprehensive study addressing the humanitarian crisis of cancer in low-resource regions across the globe. The commission has a distinguished body of experts hailing from Europe, Asia, Africa, South America, and Oceania as its members.

The Lancet Commission will convene its inaugural meeting in London from November 15-17, 2023, followed by a subsequent gathering in Toronto in 2024. Over the next two years (2023-2025), Dr Salins and his esteemed team will diligently analyse the underlying factors contributing to the disparity between the biomedical and humanitarian aspects of cancer care. Their mission encompasses devising strategic approaches to rectify this imbalance while examining the intricate interplay of political economy, value systems, and commercial drivers that impact resource allocation for cancer research, education, and clinical care.

As a professor and head of the Palliative Medicine Department at Kasturba Medical College Manipal, coordinator of Manipal Comprehensive Cancer Care Centre, and associate dean of Research, Dr Naveen Salins brings a wealth of expertise and experience to this critical endeavour. His recent receipt of the prestigious international palliative care award from the European Association of Palliative at Rotterdam, Netherlands, underscores his immense clinical impact of research in the field.

This initiative marks a pivotal moment in addressing the global health burden imposed by cancer and presents a unique opportunity for India to lead and guide international efforts in mitigating the suffering caused by this debilitating disease. His leadership and the collective efforts of the Lancet Commission are poised to significantly influence international health policies concerning cancer care, resource allocation, and the alleviation of financial strains associated with cancer treatment.

Dr H S Ballal, pro-chancellor of Manipal Academy of Higher Education (MAHE) and Dr M D Venkatesh, vice-chancellor of MAHE, have congratulated Dr Naveen Salins on this remarkable achievement. Dr Sharath Rao, pro vice Chancellor – Health Sciences, MAHE, Manipal and Dr Padmaraj Hegde, dean of Kasturba Medical College, Manipal have commended Dr Salins’s for his dedication and expertise in advancing cancer care and research. They have expressed confidence that Dr Salins’s role as the commissioner of the Lancet Commission will yield transformative outcomes in the field of cancer care and beyond.

source/content: daijiworld.com (headline edited)

KARNATAKA: Lifetime Achievement Award For Dr. H. Basavanagowdappa, Physician & Principal/Dean of JSS Medical College, Mysuru

The Association of Physicians of India, Karnataka Chapter, presented the “Lifetime Achievement Award” to Dr. H. Basavanagowdappa, a Senior Physician, Principal of JSS Medical College and Dean, Faculty of Medicine at JSS Academy of Higher Education and Research, Mysuru, at the awards ceremony held on Aug. 11 at Vijayanagara Institute of Medical Sciences, Ballari, during the Annual State Conference of the Association of Physicians of India, Karnataka State Chapter. 

The award was given in recognition of his 36 years of dedicated teaching experience in Medical education and his commitment to health services to several thousands of needy patients.

He was honoured with a plaque and a citation.

source/content: starofmysore.com (headline edited)

KARNATAKA: AI in HEALTH & MEDICAL SERVICES / OPTHALMOLOGY: AI can Predict Severity of Conjunctivitis, says Dr. Rohit Shetty, Narayana Nethralaya, Bengaluru

Addressing reporters on Thursday, the doctor said that using imaging and molecular diagnostics has enabled them to use AI and bio-markers in conjunctivitis to predict severity.

 In an effort to identify and treat severe conjunctivitis cases early, Narayana Nethralaya has managed to predict the severity of such cases using Artificial Intelligence (AI). “We are using AI to predict the severity of conjunctivitis. This can help clinicians provide the right treatment that helps in better recovery. This bio-marker work in tears is probably one of the first in the country, and could also be one of the first conjunctivitis-related tear bio-marker research in the world,” said Dr Rohit Shetty, chairman, Narayana Nethralaya explained. 

Addressing reporters on Thursday, the doctor said that using imaging and molecular diagnostics has enabled them to use AI and bio-markers in conjunctivitis to predict severity. This AI-driven research has highlighted that people who are more prone to allergies or asthma and have low Vitamin D levels are getting severely affected. The AI model has demonstrated 97 per cent accuracy, affirming its successful interpretation.

Cases of conjunctivitis, commonly known as ‘pink eye’, are on the rise in Bengaluru in the past few weeks. Doctors at Narayana see over 100 patients daily, with 30% of them being children. Most cases are caused due to adenovirus, and is not just a summer infection, but occurs in all seasons.

“This research is of paramount importance to patients and doctors, as the disease has been addressed with a blanket approach that may not be suitable for all. Depending on the severity, we can decide what medications would be suitable, and starting topical steroids early can be beneficial,” said Dr Gairik, consultant of cornea and refractive surgery, Narayana Nethralaya.

source/content: newindianexpress.com (headline edited)

NATIONAL & KARNATAKA: HEALTH & MEDICAL SERVICES /INNOVATION: Patent Won for Medicinal Patch by Scientists of BLDE University

A team of scientists from BLDE Deemed University has won a patent for an innovative method of administering drugs to patients.

The Patent Office, Union government, has granted patent for 20 years, under the Patents Act.

The patent has been granted for the development of “pharmaceutical formulations of electro-responsive smart hydrogel for transdermal drug delivery”.

The patent applicant is Raghavendra V. Kulkarni, Registrar of the university and pharmaceutical scientist.

His team from the Sri Sanganabasava Mahaswami College of Pharmacy includes Sudha B. Patil, Krishnacharya Akkamanchi and Kushal K. Das.

The patented method involves reaching medicine to targeted organs through the skin, at regulated timings, through a patch applied on the skin. The method is expected to ensure painless drug delivery at affordable prices. It is scalable, said a release.

source/content: thehindu.com (headline edited)

NATIONAL: KARNATAKA: HEALTH & PHARMACEUTICALS: Biocon Biologics’ HULIO, a Humira biosimilar now available in US for Rheumatoid Arthritis Patients

The company also offers a robust patient support programme — HULIO360, providing benefits like verification and prior authorisation support, copay assistance, a bridge programme for eligible patients.

Biocon Biologics Ltd has announced that HULIO (adalimumab-fkjp) injection, a biosimilar for Humira (adalimumab) — used to treat rheumatoid arthritis — is now available for patients in the US, after five years of experience in Europe and two years in Canada.

HULIO meets the rigorous biosimilar approval standards of the FDA. Like Humira, HULIO is citrate-free and is made without natural rubber latex (to help reduce hypersensitivity reactions). The company also offers a robust patient support programme — HULIO360, providing benefits like verification and prior authorisation support, copay assistance, a bridge programme for eligible patients, and at-home nurse injection training.

“The launch of HULIO, our biosimilar adalimumab, is an important milestone as it expands our well-known biosimilar product offering to patients in the United States. This launch builds on our strong presence in oncology and diabetes and reaffirms our commitment to enabling affordable access to biologics,” said Shreehas Tambe, CEO and MD, Biocon Biologics Ltd.  

“We are pleased to make HULIO, a patient-friendly, two-click, pre-filled pen available in the US for patients with certain inflammatory diseases,” said Mathew Erick, Chief Commercial Officer of Advanced Markets, Biocon Biologics Ltd.

source/content: newindianexpress.com (headline edited)

NATIONAL & KARNATAKA : INVENTIONS / RESEARCH / INNOVATIONS: 04 More New CSIR-CFTRI’s Technologies released in Mysuru

An anti-obese Barley-Seaweed based supplement ‘SeaSlim’, which is supposed to regulate body weight and manages obesity, has also been launched.

In the last seven decades, the Mysuru-based CSIR-CFTRI has developed nearly 400 technologies and over 4,500 licencees’ commercialised several technologies that were transferred to them by the premier institute.

On an average, 15 to 20 technologies were developed at the CFTRI annually and nearly 120-125 technologies were transferred every year, according to scientists.

At ‘One Week One Lab’ initiative that got off to a start at CFTRI here on Monday, July 3, four new technologies were launched by the dignitaries at the inaugural of OWOL. The CFTRI has proposed to release a total of 22 technologies during the weeklong OWOL.

The four technologies include barley-seaweed based anti-obese supplement ‘SeaSlim’; freshness keeper paper under the CSIR’s Floriculture Mission; process for the production of soluble and insoluble arabinoxylan from wheat bran, and production of baker’s yeast.

Freshness keeper paper is made with natural bioactive compounds. It can extend the shelf life of cut roses by 1-2 times longer, the CFTRI said.

A simple paper-based freshness keeper paper – a patented technology which is a chemical-free design to keep cut flowers fresh during transport and storage without disturbing the protocol of cut rose flowers. Freshness keeper technology is a paper wrapped with direct contact with rose flower petals that help enhance fresh-cut flowers’ quality and shelf life by two folds, a note said here.

During the export and transportation time, cut rose flowers have a shelf life of 10-12 days at 4 degrees C. With freshness paper, the shelf life is increased by 6-7 days – taking the total shelf life to 18-20 days.

“The scope of this technology is useful to Indian florists as well as other countries, more significantly who are in import and export of cut flowers as India is ranked 15th in the export of cut roses.”

This tech is chemical-free and inexpensive, reduces waste, and increases revenue. The tech helps farmers, importers, exporters and big and small vendors, the note added.

According to CFTRI, India is ranked third in the world in the prevalence of obesity. Owing to rising obesity cases, anti-obese foods are flooding the markets. The CFTRI has developed a barley-seaweed based anti-obese supplement called ‘SeaSlim’ having qualities of brown algae and barley for managing obesity. “SeaSlim can be used as a potent antioxidant food. It lowers fat absorption in the small intestine. It lowers the risk of obesity and diabetes. It helps in regulation of body weight by reducing the food intake and can be used as a low-glycemic index food. It can be recommended as a thermogenic food to manage obesity,” the release issued by CFTRI said.

source/content: thehindu.com (headline edited)

REGIONAL: KARNATAKA: HEALTH & MEDICAL SERVICES: South India’s First Vertebral Stentoplasty Conducted at Bengaluru’s Aster CMI Hospital

A stent was inserted along with the balloon in the vertebrae, and the balloon was inflated later to raise the collapsed vertebra.

 A 57-year-old woman, having suffered a spine fracture along with rheumatoid arthritis, underwent a vertebral body stenting procedure at city-based Aster CMI Hospital. This is claimed to be the first such surgery performed in South India.  

The woman was brought to the hospital in severe pain and was even unable to walk. With her limited mobility, the doctors decided to perform a vertebral body stenting procedure (stentoplasty), which was minimally invasive. Dr Umesh Srikantha, Sr Consultant – Neurosurgery, Head of Spine Services, Aster CMI Hospital, explained: “The surgery was minimally invasive and was performed using the latest medical procedure in vertebral augmentation which gave immediate relief to the patient, who was able to walk in less than 24 hours. Balloon Kyphoplasty prevents the vertebral body from collapsing and also helps in vertebral body height restoration and shape.”

A stent was inserted along with the balloon in the vertebrae, and the balloon was inflated later to raise the collapsed vertebra.

The cavity formed after deflating the balloon, and was filled with bone cement to support the bone surrounding, Dr Srikantha explained. The whole procedure was completed within an hour and the patient saw significant improvement. She was able to walk comfortably without any assistance, he added. 

S Ramesh Kumar, CEO of Aster CMI Hospital proudly called it South India’s first such surgery conducted at their hospital, which was made possible with the help of high-end technology. 

source/content: newindianexpress.com (headline edited)

KARNATAKA: HEALTH & MEDICAL SERVICES / INNOVATION: First-of-its-kind Innovative Endoscopy Procedure conducted at Kasturba Medical college, Udupi

 A team of doctors from the department of gastroenterology and hepatology – Dr Shiran Shetty (prof and head) Dr Ganesh Bhat, Dr Atish Shetty, Dr Balaji and Dr Sandesh Shet (anaesthesia) performed a complex innovative endoscopy procedure called – endoultrasound guided gastrojejunostomy – GJ for a person with gastric outlet obstruction due to underlying cancer. This procedure is less invasive than surgery and can be done and patients who are not fit for any surgery can be discharged the next day and is very cost-effective. 

A 55-year-old man with pancreatic cancer and gastric outlet obstruction with persistent vomiting was referred from another hospital. After evaluation and discussion with the team and relatives, we decided to perform a unique endoscopic procedure called EUS –gastrojejunostomy (the connection between the stomach and small intestine) for easy passage of food. The patient could tolerate oral feeds after the procedure.

This is the first-of-its-kind done in the coastal belt of Karnataka.

Dr Shiran Shetty, professor and head department of gastroenterology and Hepatology and Deputy Medical Superintendent said, “Due to newer technology more endoscopy procedures can be done for treatment of various complex diseases and is patient friendly and very cost effective.

Kasturba Hospital, Manipal is one of the first medical college hospital in India to utilize newer endoscopy technology for the management of patients from rural and poor backgrounds

Dr Anand Venugopal, chief operating officer, Teaching Hospital MAHE, Manipal praised the team of doctors and staff who were involved in this innovative procedure.

Dr Avinash Shetty, medical superintendent, Kasturba Hospital, Manipal said, “Currently, the department of gastroenterology and Hepatology at Kasturba Hospital, Manipal performs all major and complex endoscopic procedures equivalent to reputed national and international centers and it gives new hopes to the patients of coastal and middle Karnataka.”

source/content: daijiworld.com (headline edited)

KARNATAKA: INNOVATION – MEDICAL SERVICES / RESEARCH: Detect Diabetes with a Simple Antigen Test, says IISc study

Currently, researchers rely on Radioimmunoassay (RIA) to detect somatostatin levels which use radioactive materials and need to be carried out in labs only.

Detecting diabetes can become as simple as taking a rapid antigen test for Covid-19.  Researchers at the Indian Institute of Science (IISc) have discovered that fluctuations in levels of other hormones such as somatostatin,  secreted by the pancreas, can have a major impact on developing diabetes. 

Scientists argue that usually one gets diagnosed with diabetes when they have high blood glucose levels either because their pancreas does not produce sufficient insulin, or their body cells do not respond to signals from insulin that tell them to use up glucose. This can be avoided by keeping levels of somatostatin in check and potentially detecting diabetes sooner. “Changes in somatostatin secretion can be one of the first signs of diabetes,” said Nikhil Gandasi, Assistant Professor, IISc. 

Somatostatin is secreted by specific cells of the pancreas, called delta cells. “It regulates insulin and glucagon which is another hormone that works hand-in-hand with insulin to maintain blood sugar levels,” said the study.  

Researchers found that when a person is diabetic, their body will secrete less delta cells which means less Somatostatin hormone. The experiment was conducted in pancreatic cells extracted from both mice and humans. The study was published in International Journal of Molecular Sciences called ‘Somatostatin Containing delta-Cell Number Is Reduced in Type-2 Diabetes.’

The team used artificially synthesised somatostatin to test its binding against several commercially available antibodies, in order to identify the one that bound to it most efficiently, which was used to develop the assay.  Similar to the Covid-19 rapid antigen test, the kit works like the standard Enzyme-Linked Immunosorbent Assay that uses antibody-coated plates to identify the presence of antigens in a sample.

Currently, researchers rely on Radioimmunoassay (RIA) to detect somatostatin levels which use radioactive materials and need to be carried out in labs only. “The procedure also takes three days to complete,” said Caroline Miranda, another first author and post-doctoral fellow at the University of Gothenburg.” The new kit will use less blood plasma compared to the RIA method. Researchers are developing the kit into a simple hand-held device that can be mass-produced.   

source/content: newindianexpress.com (headline edited)

KARNATAKA: HEALTH SERVICES / CARDIOLOGY : Initiative offering ‘Cardiologists At Doorsteps’ of Patients launched in Dakshina Kannada

The Dakshina Kannada Zilla Pachayat, Health and Family Welfare Department, and Cardiology At Door Steps (CAD) Foundation jointly launched ‘Hrudaya Vaishalaya’, an initiative offering free consultation services of cardiologists at the doorsteps of people in the district.

As part of the initiative, cardiologists from the CAD Foundation will visit a primary health centre or a community health centre every Wednesday and conduct heart check-up of people from morning till noon. Apart from the check-up, people will be enlightened on lifestyle management.

District Health and Family Welfare officer M. Kishore Kumar said that ‘Hrudaya Vaishalya’ scheme is the extension of CAD Foundation’s initiative under which it has provided ECG machines and other ancillary machines to primary health centres for early diagnosis of cardiac problems. The latter was launched two years ago and CAD has so far provided ECG and other machines to 70% of 73 primary and community health centres in Dakshina Kannaada, Dr. Kumar said.

The first camp under the ‘Hrudaya Vaishalya’ scheme was held in the government health centre in Moodbidri on Wednesday. Inaugurating the camp, Zilla Panchayat Chief Executive Officer Kumara said Dakshina Kannada is the first district in the State to launch this unique health service. The new programme is a part of the initiative of the government to take health services closer to people, he said.

Founder of the CAD Foundation and senior cardiologist M. Padmanabha Kamath said that he wants to spread ‘Hrudaya Vaishalya’ initiative across the State. Health officers and people should be actively involved to take this initiative to all needy persons.

The next ‘Hrudaya Vaishalya’ camp will be held in a primary health centre in Puttur taluk, Dr. Kishore Kumar said.

source/content: thehindu.com (headline edited)